Asian Journal of Transfusion Science
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CASE REPORT
Year : 2015  |  Volume : 9  |  Issue : 1  |  Page : 92-93

Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases


1 Department of Transfusion Medicine, Citizens Hospital, Nallagandla, Serilingampally, Hyderabad, India
2 Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Ashish Jain
Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-6247.150964

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Most anti-N antibodies are naturally occurring, IgM antibodies, and not active above 25°C and are not clinically significant but IgG anti- N has also been described. Immune anti-N resulting from multiple transfusions does occur & has been implicated as the cause of hemolytic transfusion reactions and mild hemolytic disease of fetus and newborn. Anti- N reacting at room temperature can be a cause for ABO blood group discrepancy


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2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006