Asian Journal of Transfusion Science
Home About Journal Editorial Board Search Current Issue Ahead of print Back Issues Instructions Subscribe Login  Users: 189 Print this page  Email this page Small font sizeDefault font sizeIncrease font size 
ORIGINAL ARTICLE
Year : 2017  |  Volume : 11  |  Issue : 2  |  Page : 95-101

Factors influencing transfusion requirement in patients undergoing first-time, elective coronary artery bypass graft surgery


1 National Blood Centre, Kuala Lumpur, Malaysia
2 Laboratory and Blood Services Department, National Heart Institute, Kuala Lumpur, Malaysia
3 Advanced Medical and Dental Institute, Universiti Sains Malaysia, Pulau Pinang, Malaysia
4 Department of Anaesthesiology, National Heart Institute, Kuala Lumpur, Malaysia
5 Community and Family Case Studies, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia

Correspondence Address:
Ailin Mazuita Mazlan
National Blood Centre, Jalan Tun Razak - 50400 Kuala Lumpur
Malaysia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ajts.AJTS_51_16

Rights and Permissions

Context: Coronary artery bypass graft (CABG) operation is associated with high frequency of allogeneic blood transfusion due to the acquired hemostatic challenges in patients undergoing CABG. However, allogeneic blood transfusion carries risks of infection, adverse reaction, and mortality as well as prolonged hospital stay and increased hospital cost. It is important to identify patients who require blood transfusion to mitigate their risk factors and reduce the chance of exposure to allogeneic blood. Aims: This study was conducted to evaluate factors that influence the decision to transfuse red cell in first-time elective CABG patients. Settings and Design: This was a cross-sectional study based on a retrospective record review. The study was done in the National Heart Institute. Materials and Methods: All patients who underwent first-time elective CABG were included in this study. Variables analyzed include age, gender, body weight, preoperative hemoglobin (Hb) level, patients' comorbidities, and other clinical parameters. Statistical Analysis Used: Data were analyzed using SPSS software version 20. Results: A total of 463 patients underwent first-time elective CABG during the period of the study. Three hundred and eighty-six (83.4%) patients received red cell transfusion. From multiple logistic regression analysis, only age (odds ratio [OR] = 1.040, 95% confidence interval [CI]: 1.003, 1.077, P = 0.032), body weight (OR = 0.951, 95% CI: 0.928, 0.974, P < 0.001), Hb level (OR = 0.500, 95% CI: 0.387, 0.644, P < 0.001), and cardiopulmonary bypass time (OR = 1.013, 95% CI: 1.004, 1.023, P < 0.001) were the significant independent predictors of red cell transfusion. Conclusions: By stratifying patients according to their risk factor for red cell transfusion, the high-risk patients could be recognized and should be enrolled into effective patient blood management program to minimize their risk of exposure to allogeneic blood transfusion.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed169    
    Printed1    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal

 

Association Contact us | Sitemap | Advertise | What's New | Feedback | Copyright and Disclaimer

2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006