Asian Journal of Transfusion Science

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 13  |  Issue : 2  |  Page : 90--94

Role of plasma exchange in postpartum microangiopathies: An experience from a tertiary care center


Rekha Hans1, Satya Prakash1, Divjot Singh Lamba1, Ratti Ram Sharma1, Pankaj Malhotra2, Vanita Suri3, Neelam Marwaha1 
1 Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Obstetrics and Gyneacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Ratti Ram Sharma
Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh
India

BACKGROUND: Postpartum microangiopathies are rare but are associated with high maternal and fetal mortality requiring early diagnosis and prompt treatment to improve the outcome. AIMS AND OBJECTIVES: This retrospective study aims to assess the efficacy of plasma exchange (PE) therapy in postpartum thrombotic microangiopathies. MATERIALS AND METHODS: We did retrospective analysis of all plasma exchange procedures performed in patients of postpartum thrombotic microangiopathies over a period of 1 year (2015-2016). Patient's pre- and post-plasma exchange hematological and biochemical parameters were recorded and compared for analyzing the response to the therapy. Patients were followed telephonically even after their discharge from the hospital. RESULTS: Hematological and renal profile improved in 8 out of 9 patients after PE therapy. Survival after PE therapy was 40% in post partum atypical HUS and 75% in patients with HELLP syndrome at 4 months of follow up. CONCLUSION: Early initiation of PE therapy in postpartum thrombotic microangiopathies can reduce morbidity and mortality associated with them.


How to cite this article:
Hans R, Prakash S, Lamba DS, Sharma RR, Malhotra P, Suri V, Marwaha N. Role of plasma exchange in postpartum microangiopathies: An experience from a tertiary care center.Asian J Transfus Sci 2019;13:90-94


How to cite this URL:
Hans R, Prakash S, Lamba DS, Sharma RR, Malhotra P, Suri V, Marwaha N. Role of plasma exchange in postpartum microangiopathies: An experience from a tertiary care center. Asian J Transfus Sci [serial online] 2019 [cited 2020 Jul 10 ];13:90-94
Available from: http://www.ajts.org/article.asp?issn=0973-6247;year=2019;volume=13;issue=2;spage=90;epage=94;aulast=Hans;type=0