| CASE REPORT |
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| Year : 2009 | Volume
: 3
| Issue : 1 | Page : 26-27 |
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Hyperhemolysis in a patient with β-thalassemia major
R Lakmali Morawakage1, B.J.C Perera2, P.D.N Dias2, SK Wijewardana2
1 Transfusion Medicine, National Blood Centre, Sri Lanka
2 Lady Ridgeway Children Hospital, Sri Lanka
Correspondence Address:
R Lakmali Morawakage
Transfusion Medicine, National Blood Centre
Sri Lanka
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0973-6247.45259
Clinical trial registration None
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A case of hyperhemolysis in a 2-year-old boy with β thalassemia major was noted. After several transfusions, he developed hyperhemolysis with a positive (C3d only) direct antiglobulin test (DAT) and no clinically significant RBC allo- or auto-antibodies. (There was a weak cold antibody, showing a narrow thermal range). Because there was no significant improvement with steroid and immunoglobulin infusions, cyclophosphamide therapy was tried with notable success. |
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