Asian Journal of Transfusion Science
Home About Journal Editorial Board Search Current Issue Ahead of print Back Issues Instructions Subscribe Login  Users: 1408 Print this page  Email this page Small font sizeDefault font sizeIncrease font size 

LETTER TO THE EDITOR Table of Contents   
Year : 2013  |  Volume : 7  |  Issue : 2  |  Page : 163-164
Profile of deferral of blood donors in regional blood transfusion center in North India

1 UCMS and Associated GTB Hospital, Bhopal, India
2 All India Institute of Medical Sciences, Bhopal, India

Click here for correspondence address and email

Date of Web Publication25-Jul-2013

How to cite this article:
Sharma T, Singh B, Bhatt GC. Profile of deferral of blood donors in regional blood transfusion center in North India. Asian J Transfus Sci 2013;7:163-4

How to cite this URL:
Sharma T, Singh B, Bhatt GC. Profile of deferral of blood donors in regional blood transfusion center in North India. Asian J Transfus Sci [serial online] 2013 [cited 2023 Mar 30];7:163-4. Available from:


Safety of blood and blood products is a major problem all over the world. Stringent donor screening criteria are designed to protect both the blood donor and recipient from harm. The present study was conducted with an objective to assess the current rate and reasons for donor deferral, and to guide the proposed donor education and recruitment strategy.

A retrospective analysis of data of blood donors presenting in our hospital was done from January 2011 to June 2011. Deferral reasons were analyzed among replacement/voluntary, male/female, various age group categories, and whether deferral was temporary or permanent.

A total of 19,125 donors presented in the hospital and voluntary donation camps during the study period, out of which 18,343 (95.9%) were males and 782 (4.1%) females. There were 5224 (27.3%) replacement and 13,901 (72.7%) voluntary donors. Total number of deferred donors were 976 (5.1%), and the deferral rate was comparable with earlier reports, [1],[2] however, deferral rate as high as 16.4% has been reported. [3]

Out of the total 976 deferred donors, 720 (73.8%) were males and 256 (26.2%) females, the rate of deferral being significantly higher for females than that for males (32.7% and 3.92%, respectively, P < 0.001). There was significant difference in rates of deferral in replacement and voluntary donors (13.5% and 2%, respectively, P < 0.001). Agnihotri found that the related donors had a significantly low deferral rate as compared with voluntary donors. [4] Rates of deferral increased significantly as the age increased (P < 0.001). There were 864 (88.5%) temporary and 112 (11.5%) permanent deferrals out of the 19,125 donors (P = 0.339), which was similar to reports from earlier studies. [1],[3]

In our study, overall, the most common cause of deferral was low hemoglobin (49.7%), similar to earlier studies [1],[2],[3],[4] followed by ongoing medication(s) (11.8%), intake of alcohol within 24 hours (8.6%), and fever and/or infection (5.5%) [Table 1]. Majority of such donors were aged 26-35 years [Table 2].
Table 1: Distribution of common causes of deferral by sex and replacement/voluntary

Click here to view
Table 2: Deferral reason comparison in different age group donors

Click here to view

The most common cause of permanent deferral was hypertension and cardiovascular problems (3.8%), followed by history of jaundice/hepatitis B/C (3.3%) [Table 1]. Those deferred due to hypertension/cardiovascular problems were mostly aged 36-55 years and were mostly males [Table 2]. Previous studies have reported hypertension [1],[4],[5] as the most common cause of permanent deferral whereas others have reported history of jaundice [6] as the most common cause.

In conclusion, variations in rates of donor deferral may be attributed to different donor selection criterion in different regions and centers. Efforts must be taken to increase awareness among deferred donor and encouraging them for future donation to reduce much of the loss of useful units of blood. Raising general awareness for blood donation and encouraging related donors to become regular donors may help increase the number of voluntary donations. Donor recruitment strategies with more liberal criterion may reduce the number of deferrals.

   References Top

1.Sundar P, Sangeetha SK, Seema DM, Marimuthu P, Shivanna N. Pre-donation deferral of blood donors in South Indian set-up: An analysis. Asian J Transfus Sci 2010;4:112-5.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.Rabeya Y, Rapiaah M, Rosline H, Ahmed SA, Zaidah WA, Roshan TM. Blood pre-donation deferrals-a teaching hospital experience. Southeast Asian J Trop Med Public Health 2008;39:571-4.  Back to cited text no. 2
3.Bahadur S, Jain S, Goel RK, Pahuja S, Jain M. Analysis of blood donor deferral characteristics in Delhi, India. Southeast Asian J Trop Med Public Health 2009;40:1087-91.  Back to cited text no. 3
4.Agnihotri N. Whole blood donor deferral analysis at a center in Western India. Asian J Transfus Sci 2010;4:116-22.  Back to cited text no. 4
[PUBMED]  Medknow Journal  
5.Jashnani KD, Patil LN. Blood donor deferrals: Can this be reduced? Asian J Transfus Sci 2011;5:60.  Back to cited text no. 5
[PUBMED]  Medknow Journal  
6.Kaur R, Basu S, Marwaha N. A Reappraisal of underlying causes in donor deferral. Ann Natl Acad Med Sci 2002;38:93-9.  Back to cited text no. 6

Correspondence Address:
Tanya Sharma
20/19, Third floor, Old Rajendra Nagar, New Delhi
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-6247.115603

Rights and Permissions


  [Table 1], [Table 2]

This article has been cited by
Anu J, Nabeel Azeez K, Apuca Susan Mathew
[Pubmed] | [DOI]



    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Email Alert *
    Add to My List *
* Registration required (free)  

    Article Tables

 Article Access Statistics
    PDF Downloaded66    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

Association Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer | Privacy Notice

2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006