Asian Journal of Transfusion Science
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CASE REPORT
Year : 2020  |  Volume : 14  |  Issue : 2  |  Page : 185-186

Hereditary persistence of fetal hemoglobin


1 Department of Pathology, Blood Bank, Component and Aphaeresis Unit, G. R. Medical College, Gwalior, Madhya Pradesh, India
2 Lal Pathology, SDM Road, Gwalior, Madhya Pradesh, India
3 Department of Pathology, G. R. Medical College, Gwalior, Madhya Pradesh, India

Correspondence Address:
Dr. Dharmesh Chandra Sharma
2-B, J. A. Hospital Campus, Gwalior - 474 009, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ajts.AJTS_71_16

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Hereditary persistence of fetal hemoglobin (HPFH) is a benign condition in which significant fetal hemoglobin production continues well into adulthood, disregarding the normal shutoff point after which only adult-type hemoglobin should be produced. The percentage of incorrect expression might be as low as 10%–15% or as high as 100% of the total hemoglobin, usually higher in homozygotes than in heterozygotes. The present case is a typical example of homozygous HPFH.


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2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006