Asian Journal of Transfusion Science
Home About Journal Editorial Board Search Current Issue Ahead of print Back Issues Instructions Subscribe Login  Users: 243 Print this page  Email this page Small font sizeDefault font sizeIncrease font size 
CASE REPORT
Year : 2020  |  Volume : 14  |  Issue : 2  |  Page : 195-197

Extensive iron overload in bone marrow: A cause of pancytopenia in a thalassemia major patient – A case report


1 Section of Haematology, Department of Pathology, Jinnah Medical College, Karachi, Pakistan
2 Section of Haamatology, Laboratory, Patel Hospital, Karachi, Pakistan
3 Section of Haematology, Department of Pathology, Dow University of Health Sciences, Karachi, Pakistan

Correspondence Address:
Dr. Sidra Asad Ali
Patel Hospital, St. 18, Block 4, Gulshan-e-iqbal, Karachi
Pakistan
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ajts.AJTS_11_18

Rights and Permissions

Iron overload-associated organ damage in transfusion-dependent anemias is a well-known phenomenon. Here, we discuss a case of 28-year-old, poorly chelated thalassemia major patient, whose blood workup revealed pancytopenia and moderately raised serum ferritin levels. His bone marrow examination was performed which revealed massive iron overload. Aggressive iron chelation led to successful recovery of peripheral blood counts in his patient. This case focuses on the importance of early detection and timely management of reversible iron overload toxicities. Serum ferritin although is convenient marker to asses iron overload, but it should not be relied upon to assess the severity of iron overload. Hence, organ-specific diagnostic modalities must be used along with serum ferritin to assess the severity of iron overload to prevent long-term complications in patients with regular blood transfusions.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed452    
    Printed10    
    Emailed0    
    PDF Downloaded5    
    Comments [Add]    

Recommend this journal

 

Association Contact us | Sitemap | Advertise | What's New | Feedback | Copyright and Disclaimer

2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006