Asian Journal of Transfusion Science

REVIEW ARTICLE
Year
: 2016  |  Volume : 10  |  Issue : 1  |  Page : 12--21

Use of lectins in immunohematology


Ajit C Gorakshakar, Kanjaksha Ghosh 
 Department of Transfusion Medicine, National Institute of Immunohaematology, KEM Hospital Campus, Mumbai, Maharashtra, India

Correspondence Address:
Ajit C Gorakshakar
National Institute of Immunohaematology, 13th Floor, New Multistoried Building, KEM Hospital Campus, Parel, Mumbai - 400 012, Maharashtra
India

Lectins are carbohydrate binding proteins present in seeds of many plants, especially corals and beans, in fungi and bacteria, and in animals. Apart from their hemagglutinating property, a wide range of functions have been attributed to them. Their importance in the area of immunohematology is immense. They are used to detect specific red cell antigens, to activate different types of lymphocytes, in order to resolve problems related to polyagglutination and so on. The introduction of advanced biotechnological tools generates new opportunities to exploit the properties of lectins, which were not used earlier. Stem cell research is a very important area in transplant medicine. Certain lectins detect surface markers of stem cell. Hence, they are used to understand the developmental biology of stem cells. The role of various lectins in the areas of transfusion and transplant medicine is discussed in detail in this review.


How to cite this article:
Gorakshakar AC, Ghosh K. Use of lectins in immunohematology.Asian J Transfus Sci 2016;10:12-21


How to cite this URL:
Gorakshakar AC, Ghosh K. Use of lectins in immunohematology. Asian J Transfus Sci [serial online] 2016 [cited 2021 Sep 21 ];10:12-21
Available from: https://www.ajts.org/article.asp?issn=0973-6247;year=2016;volume=10;issue=1;spage=12;epage=21;aulast=Gorakshakar;type=0