Asian Journal of Transfusion Science

CASE REPORT
Year
: 2016  |  Volume : 10  |  Issue : 2  |  Page : 152--154

Anti IH: An antibody worth mention


Nithya Mohanan, Nittin Henry, Aboobacker Mohamed Rafi, Susheela J Innah 
 Department of Transfusion Medicine, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India

Correspondence Address:
Nithya Mohanan
Department of Transfusion Medicine, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala
India

A 72-year-old female with co-morbidities posted for surgical correction of fracture neck of femur without any history of transfusions was noted to have a hemoglobin level of 7 g/dl and packed red blood cells transfusion was ordered. Pretransfusion tests demonstrated A1B group with D positive on forward grouping. Reverse grouping showed a varying grade of agglutination with A, B, and O cells. Agglutination being stronger at 4°C. Antibody screening showed pan-agglutination, direct Coomb's test and auto control were negative. The serum reacted with adult O cells (OIadult) but not with adult Bombay cells (Oh Iadult) or O cord (Oicord) cells. A possibility of a compound cold antibody anti IH was made and A1B compatible cells were transfused to the patient. This case report illustrates anti-IH cold agglutinin with broad thermal amplitude. Uniqueness of this case report was O group incompatibility with A1B group, which was detected earlier and a catastrophic transfusion reaction being subverted.


How to cite this article:
Mohanan N, Henry N, Rafi AM, Innah SJ. Anti IH: An antibody worth mention.Asian J Transfus Sci 2016;10:152-154


How to cite this URL:
Mohanan N, Henry N, Rafi AM, Innah SJ. Anti IH: An antibody worth mention. Asian J Transfus Sci [serial online] 2016 [cited 2021 Sep 23 ];10:152-154
Available from: https://www.ajts.org/article.asp?issn=0973-6247;year=2016;volume=10;issue=2;spage=152;epage=154;aulast=Mohanan;type=0