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  Indian J Med Microbiol
 

Figure 1: RRx-001 increases nitric oxide (NO) generation in two ways: (i) As an NO donor: Through metabolism of the dinitro groups released from the compound, and (ii) as an NO promoter: RRx-001 modifies beta subunits cysteine 93 increasing nitrite reduction to NO by deoxyhemoglobin

Figure 1: RRx-001 increases nitric oxide (NO) generation in two ways: (i) As an NO donor: Through metabolism of the dinitro groups released from the compound, and (ii) as an NO promoter: RRx-001 modifies beta subunits cysteine 93 increasing nitrite reduction to NO by deoxyhemoglobin